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PDF) Design and development of masked therapeutic antibodies to limit  off-target effects Application to anti-EGFR antibodies
PDF) Design and development of masked therapeutic antibodies to limit off-target effects Application to anti-EGFR antibodies

Ab locks for improving the selectivity and safety of antibody drugs |  Journal of Biomedical Science | Full Text
Ab locks for improving the selectivity and safety of antibody drugs | Journal of Biomedical Science | Full Text

Ab locks for improving the selectivity and safety of antibody drugs |  Journal of Biomedical Science | Full Text
Ab locks for improving the selectivity and safety of antibody drugs | Journal of Biomedical Science | Full Text

The Masking Game: Design of Activatable Antibodies and Mimetics for  Selective Therapeutics and Cell Control | ACS Central Science
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control | ACS Central Science

Design and development of masked therapeutic antibodies to limit off-target  effects: application to anti-EGFR antibodies. - Abstract - Europe PMC
Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies. - Abstract - Europe PMC

Tunable modulation of antibody‐antigen interaction by protease cleavage of  protein M - Kim - 2019 - Biotechnology and Bioengineering - Wiley Online  Library
Tunable modulation of antibody‐antigen interaction by protease cleavage of protein M - Kim - 2019 - Biotechnology and Bioengineering - Wiley Online Library

The Masking Game: Design of Activatable Antibodies and Mimetics for  Selective Therapeutics and Cell Control | ACS Central Science
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control | ACS Central Science

The Masking Game: Design of Activatable Antibodies and Mimetics for  Selective Therapeutics and Cell Control | ACS Central Science
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control | ACS Central Science

Technology Platforms
Technology Platforms

Selective antibody activation through protease-activated pro-antibodies  that mask binding sites with inhibitory domains | Scientific Reports
Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains | Scientific Reports

PDF] A Search for the Masked Mechanism Behind IgG-Mediated Suppression of  Antibody Responses | Semantic Scholar
PDF] A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses | Semantic Scholar

Selective antibody activation through protease-activated pro-antibodies  that mask binding sites with inhibitory domains | Scientific Reports
Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains | Scientific Reports

The Masking Game: Design of Activatable Antibodies and Mimetics for  Selective Therapeutics and Cell Control | ACS Central Science
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control | ACS Central Science

Antibody prodrugs for cancer
Antibody prodrugs for cancer

antibody prodrug concept. (a) For proof-of-principle, eGFR domain III... |  Download Scientific Diagram
antibody prodrug concept. (a) For proof-of-principle, eGFR domain III... | Download Scientific Diagram

Ab locks for improving the selectivity and safety of antibody drugs |  Journal of Biomedical Science | Full Text
Ab locks for improving the selectivity and safety of antibody drugs | Journal of Biomedical Science | Full Text

Protease-activation using anti-idiotypic masks enables tumor specificity of  a folate receptor 1-T cell bispecific antibody | Nature Communications
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody | Nature Communications

The Role of 89Zr-Immuno-PET in Navigating and Derisking the Development of  Biopharmaceuticals | Journal of Nuclear Medicine
The Role of 89Zr-Immuno-PET in Navigating and Derisking the Development of Biopharmaceuticals | Journal of Nuclear Medicine

Steric blockade of antibody CDRs as a modular antibody masking... |  Download Scientific Diagram
Steric blockade of antibody CDRs as a modular antibody masking... | Download Scientific Diagram

The Masking Game: Design of Activatable Antibodies and Mimetics for  Selective Therapeutics and Cell Control | ACS Central Science
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control | ACS Central Science

Ab locks for improving the selectivity and safety of antibody drugs |  Journal of Biomedical Science | Full Text
Ab locks for improving the selectivity and safety of antibody drugs | Journal of Biomedical Science | Full Text

Mechanistic insights into the rational design of masked antibodies
Mechanistic insights into the rational design of masked antibodies